Dioctahedral Smectite

Product name:Dioctahedral Smectite

SYNONYMS: Montmorillonite,Montmorillonite clay,Diosmectite,Smectite,Bentonite

CAS Number:

Appearance:Off-white or gray powder

Specification:Pharmaceutical grade,with X-RAY spectrum.There are five standards available.

(1)  CP2010/2015  (2) Pharma grade In-House Standard  (3)USP  (4)EP  (5)BP

Quality Standard:CP2015 

Appearance:Off-white color powder

Identification:Meet the requirement

SiO2,%:55.0~65.0

Al2O3,%:12.0~25.0

PH:5.0-9.0

Cl-,%:NMT 0.025

Carbonate:Not detected

Water solubility salt,%:NMT 0.70

Cristobalite and other impurities:Meet the requirement

Loss on drying,%:NMT 10.0

Granularity(pass 325 mesh),%:Meet the requirement

Degree of expansion,ml/5g:2.0~5.0

Adsorption strength,g/g:0.35~0.55

Heavy metals,ppm:NMT 10

As,ppm:NMT 2

Total viable count:NMT 100

Mildew and microzyme quantity:NMT 20

Coliform groups quantity:NMT 100

Escherichia coli:Not detected

Usage:APIs of anti-diarrhoeal widely used for children and adult.It is also one of pharmaceutical excipients.Dioctahedral Smectite is the main ingredient of the medicines below (by brand name):

Grafort-Daewoong, Vietnam

Smecta-Ipsen Pharma, Myanmar

Smectivet (veterinary use)-Boehringer Ingelheim Sante Animale, France

Bedelix-Ipsen, France

Pedismec-RPG, India

Bentonitum-IFET, Greece

Peptosyl (Smectites and Bismuth Subsalicylate (veterinary use))-Vetpharm, New Zealand

Colina Spezial (Smectites and Aluminium Hydroxide-Magnesium Carbonate Co-dried Gel)-IPSEN PHARMA, Germany

Dimectil-Lafrancol, Colombia

Diosmectal-BB Farma, Italy; Farma 1000, Italy; Malesci, Italy; Medifarm, Italy

Neosmectin-Pharmstandard, Georgia

Nodia-Marvecs Pharma Services, Italy

Smecta-Beaufour Ipsen, Hong Kong; Beaufour Ipsen, Malaysia; Beaufour Ipsen, Tunisia; Ipsen,